Treatment selection for long-term success
Together, these treatment selection pillars, a framework created by Gilead, highlight considerations that may help people with HIV achieve durable viral suppression and long-term success.
Gilead believes that long-term success means attaining US Department of Health and Human Services (DHHS) treatment goals1,* for the long term.
*Once initiated, antiretroviral therapy (ART) should be continued with the following key treatment goals, as identified by the DHHS: maximally and durably suppress plasma HIV ribonucleic acid (RNA); restore and preserve immunologic function; reduce HIV-associated morbidity and prolong the duration and quality of survival; and prevent HIV transmission.1
According to the DHHS and the Office of Disease Prevention and Health Promotion (ODPHP), the social determinants of health (SDOH) are the conditions in the environments where people are born, live, learn, work, play, worship, and age that affect a wide range of health, functioning, and quality-of-life outcomes and risks. SDOH can be grouped into 5 domains, including Economic Stability, Education Access and Quality, Health Care Access and Quality, Neighborhood and Built Environment, and Social and Community Context.2
Explore a comprehensive treatment approach
HIV care that supports long-term success starts with a comprehensive approach to treatment selection.1
Consider these key attributes when selecting a treatment that could help contribute to long-term success:
References:
- Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in adults and adolescents with HIV. US Department of Health and Human Services. Updated September 12, 2024. Accessed January 8, 2025. https://clinicalinfo.hiv.gov/sites/default/files/guidelines/documents/adult-adolescent-arv/guidelines-adult-adolescent-arv.pdf
- Healthy People 2030, US Department of Health and Human Services, Office of Disease Prevention and Health Promotion. Accessed March 31, 2025. https://health.gov/healthypeople/priority-areas/social-determinants-health
- World Health Organization. Guidance for best practices for clinical trials. Updated September 2024. Accessed February 25, 2025. https://www.who.int/publications/i/item/9789240097711